Wednesday, February 19, 2020

Benefits of Exercise Research Paper Example | Topics and Well Written Essays - 1250 words

Benefits of Exercise - Research Paper Example In this essay, the various types of exercise and their effects on health will be discussed. Types of exercise There are different types of exercise and these can be categorized into 3 groups based on their intensity. They are the light exercise, moderate exercise and vigorous exercise. During light exercise, it is possible for the exerciser to talk. Walking is an example of light exercise. In moderate exercise, there is mild feeling of out of breath for the exerciser. Examples of moderate exercise include brisk walking, walking uphill and moderate cycling. During vigorous exercise, the exerciser experiences panting. Examples of this type of exercise include fast cycling, running and heavy weight training (Christian, Medical NewsToday). There are 2 types of exercise and they are aerobic and anaerobic exercises. In aerobic exercise, the aim of the exercise is to increase the oxygen consumption of the body. The exercises are usually of moderate intensity and involve large muscle groups. It involves warming up and exercise for 20 minutes, followed by cooling down. A simple example for aerobic exercise is running for 20 minutes and playing badminton for 30 minutes. On the other hand, in anaerobic exercise, the muscles are exercised at high intensities for short durations, which are less than 2 minutes. Oxygen is not used during these exercises and hence they use fewer calories than aerobic exercises (Christian, Medical NewsToday). Benefits of exercise on general health Benefits of aerobic exercise include, strengthening of respiratory muscles, thus facilitating improved inflow and outflow of air from the lungs, strengthening and enlargement of the heart muscle, thus causing lowering of heart rate during resting, toning of muscles, reduction in blood pressure, improvement in blood circulation, increase in the number of red blood cells, improvement in the quality of sleep and improvement in mental health. Other benefits include decrease in diseases like migraine, decr ease in the risk of heart disease and other cardiovascular diseases, improvement in survival rates in those with already established heart disease, stimulation of bone growth, thereby reducing the risk of osteoporosis, increase in stamina and endurance, increased ability to store fat and glycogen within muscles, increased blood flow through muscles, increased ability of the muscles to use fats during exercise, thus enhancing preservation of intramuscular glycogen. Benefits of anaerobic exercises include increase in the strength and power of muscles. They also help in strengthening of bones, protection of joints and control of body weight. Examples of anaerobic exercises are sprinting, weight lifting, interval training, intensive and fast skipping, isometrics and rapid burst of hard exercise (Christian, Medical NewsToday). There are some exercises which include a combination of muscle strengthening, stretching and balancing. A good example of such combination exercise is Yoga. Most e xperts agree that stretching itself is a good form of exercise. Yoga improves balance, movements, posture and flexibility (Christian, Medical NewsToday). The best health effect of exercise is prevention and treatment of obesity. Obesity is prevalent all over the world, particularly in the developed nations. Approximately 7% of the estimated current world population is obese (Uwaifo, Emedicine). Obesity affects all races. It is prevalent equally in both the

Tuesday, February 4, 2020

GLUT4 glucose transporter Essay Example | Topics and Well Written Essays - 2500 words

GLUT4 glucose transporter - Essay Example The generalised form of this reaction is written as follows There are three types of sugar transporters that carry sugars across the plasma membrane in to the cells. First are the energy independent facilitated diffusion transporters such as the glucose transporters family(GLUT) of hexose transporters seen in yeast and in mammalian cells. These proteins are encoded by SLC2A genes(solute carriers 2A). Second are the energy dependent transporters for example sodium dependent glucose transporters(SGLT) encoded by SLC5A genes in the intestine and in kidney epithelial cells. The third type of transporters couple ATP dependent phosphorylation with sugar import and are seen in bacteria. This family of glucose transporters were first discovered in yeast where 18 genes have been identified. Humans have 14 GLUT homologs. All of the yeast glucose transporters are of the same size(40-55 Kilodaltons) and have similar structures containing 12 membrane spanning domains. These domains form a barrel with a small pore for the sugar to pass through. The only "sugar transport signatures" are a few widely scattered glycine and tryptophan residues and one PET tri-peptide sequence The elevated levels of blood sugar and amino acids that occur following a meal signal pancreatic beta cells to release insulin into the bloodstream. Once in the vascular system, circulating insulin markedly enhances glucose transport into skeletal muscle and adipose tissue, the peripheral sites responsible for the majority of postprandial glucose disposal. In response to insulin, glucose enters muscle and fat cells through aqueous pores formed by the glucose transporter 4 (GLUT4) protein. GLUT4 is the fourth of 13 members of a family of facilitative sugar transporters and is the only iso-form that is widely accepted as being insulin-responsive. Like other GLUT family members, GLUT4 is a 12 trans-membrane protein; unlike most other isofoms, GLUT4 is predominantly localized to intracellular compartments in the basal state. Activation of the insulin receptor triggers a large increase in the rate of GLUT4 vesicle exocytosis and a concomitant decrease in the rate of endocytosis. This insulin-dependent shift in GLUT4 vesicle trafficking results in a net increase of GLUT4 protein at the cell surface, thus allowing glucose to enter target cells. Once